Improved clinical imaging of head and neck cancers - Degree project at KI
CD44v6 is an antigen overexpressed in squamous cell carcinomas, especially in the head & neck region. Previously several targeting molecules towards this antigen have been assessed for molecular imaging using PET (Positron emission tomography) with promising results. Recently, two scFv’s (single chain fragments) towards CD44v6 were selected and affinity maturated in a collaboration between UU, KI and KTH, demonstrating the best properties for molecular imaging that has been achieved so far. The group now wants to take this project further by optimizing and evaluating the top candidate for potential in molecular imaging of squamous cell carcinoma. This degree project may allow you to take part in and contribute to this important work.
Department: Dept of Radiopharmacy, Karolinska University Hospital / Dept of Clinical Neuroscience, Karolinska Institutet (KI)
Place: Solna / Stockholm
Start: Spring 2019
Application: Contact the PI!